Description:

Bruce Neal, MB, ChB, PhD

Deputy Executive Director, The George Institute for Global Health, Australia

Professor of Medicine, UNSW Sydney

Professor of Clinical Epidemiology Imperial College London, UK.

Dr. Neal is a cardiovascular epidemiologist with specific content area expertise in high blood pressure and diabetes. He has played lead roles in multiple large-scale clinical trials and meta-analyses. He also has a longstanding interest in the environmental determinants of chronic disease and the potential for changes in the food supply to deliver large, cost-effective and equitable health gains. His food policy work seeks to change the way that food is manufactured, retailed, and consumed using business and policy levers.

Presentation Title

Salt Substitute and Stroke Study

Anushka Patel
MBBS, SM, PhD, FRACP

Chief Scientist, The George Institute for Global Health,

Professor of Medicine, UNSW Sydney

Cardiologist, Royal Prince Alfred Hospital, Sydney

Dr. Patel is a general cardiologist with a research interest in clinical prevention strategies for chronic disease prevention and management, particularly in primary care settings. She has a program of both clinical research and increasingly, health systems research with current partnership projects in Australia, China, India, Indonesia, Myanmar and Sri Lanka.

Presentation Title

Primary health care based research at The George Institute for Global

Description:

Presentation Title

Biologic Pathways to Improve Walking Performance in PAD 

This special session will be a practice talk for Dr. Mary McDermott who has been nominated as an AHA Merit Award Finalist.

Mary McDermott, MD
Jeremiah Stamler Professor
Professor of Medicine and Preventive Medicine
Feinberg School of Medicine
Northwestern University

Description:

CARDIA Lung Study Renewal with Ravi Kalhan, MD, MS

Discussion of recent peer review for the competing renewal of the CARDIA Lung ancillary study and how to best respond to concerns raised by the reviewers.

Description:

Presentation Title:

Mediators of Atherosclerosis in South Asians Living in America: Cohort Description and Opportunities for Manuscripts and Ancillary Studies

Objectives:
1) Learn about the MASALA study cohort as a resource for Northwestern investigators
2) Discuss available data and process for manuscript proposals and ancillary studies
3) Discuss priority research areas

 with Namratha Kandula, MD, MPH

Associate Professor of Medicine and Preventive Medicine
Co-Director, Center for Community Health
Department of Preventive Medicine
Division of General Internal Medicine
Northwestern University
Feinberg School of Medicine

Description:

Please note the time of the presentation will be at 9:00 am-10:00 am on Monday, February 4th, 2019. Breakfast will be served. 

Special Presentation with Yanqing Wang, PhD

Candidate for the Division of Biostatistics/BCC Position

Postdoctoral Fellow
Department of Biostatistics and Biomathematics
Fred Hutchinson Cancer Research Center

Presentation Title:
Learning-based Biomarker-assisted Rules for Optimized Clinical Benefit under a Risk-constraint

Brief Abstract:
Novel biomarkers, in combination with currently available clinical information, have been sought to improve clinical decision making in many branches of medicine, including screening, surveillance, and prognosis. Statistical methods are needed to integrate such diverse information to develop targeted intervention that balances benefit and harm. In the specific setting of disease detection, we propose novel approaches to construct a multiple-marker-based decision rule by directly optimizing a benefit function, while controlling harm at a maximally tolerable level. The new approaches include plug-in and direct-optimization--based algorithms, and they allow for the construction of both nonparametric and parametric rules. A study of asymptotic properties of the proposed estimators is provided. Simulation results demonstrate good clinical utilities for the resulting decision rules under various scenarios. The methods are applied to a biomarker study in prostate cancer surveillance.